GeneChip™ technology, Stephen Fodor
Interviewee: Stephen Fodor. Stephen Fodor talks about bringing the knowledge gathered by the Human Genome Project to the individual researcher. (DNAi Location: Applications > Genes and medicine > Genetic profiling > Stephen Fodor > GeneChip™ technology)
Well, in the early '80s the decision had been made to attempt to sequence the human genome. And in the later part of that decade we were thinking about how to create a technology that could actually bring the human genome to the individual researcher. And the DNA chip technology, or the GeneChip™ technology is the technology that can actually perform that. It's a marriage of both life sciences chemistry with Silicon Valley manufacturing processes that allow you to take the basic building blocks of DNA, the A, the C, the G and the T, and build different combinations of those building blocks in order to make different strands of DNA.
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- ID: 15049
- Source: DNALC.DNAi
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15051. How GeneChip was developed (Part II), Stephen Fodor
Stephen Fodor continues his discussion of the experiments that laid the groundwork for GeneChip technology.
15050. How GeneChip was developed (Part I), Stephen Fodor
Stephen Fodor discusses the experiments that laid the groundwork for GeneChip technology.
16112. Manufacturing the gene chip, Stephen Fodor
Stephen Fodor talks about manufacturing the gene chip.
15083. Making DNA chips, Stephen Fodor
Stephen Fodor talks about the photolithographic technique used to synthesize pieces of DNA on the surface of GeneChipsÂ®.
15053. Gene profile and response to treatment, Stephen Fodor
Stephen Fodor talks about how an individual's gene expression profile can help determine what therapies might work best.
15052. Effects of DNA variation on health, Stephen Fodor
Stephen Fodor talks about the need to look broadly across the genome to find the relationship between genes and health in different people.
16114. Limit to the gene chip, Stephen Fodor.
Stephen Fodor talks about limit to the gene chip.
15038. Making a DNA microarray, Patrick Brown
Pat Brown discusses the early technology behind the microarray.
16757. Biography 36: Stephen P. A. Fodor (1953- )
Steve Fodor changed the way genomes can be screened with GeneChipsÂ®.
16113. Understanding genes and health, Stephen Fodor
Stephen Fodor talks about understanding genes and health.