Gene profile and response to treatment, Stephen Fodor
Interviewee: Stephen Fodor. Stephen Fodor talks about how an individual's gene expression profile can help determine what therapies might work best. (DNAi Location: Applications > Genes and medicine > Genetic profiling > Stephen Fodor > Gene profile and therapy)
Now at the same time we're beginning to understand some of the signatures that we may see. For example, if we look at a breast cancer sample and we understand that a particular expression profile responds to one treatment and a different expression profile responds to a different treatment, then of course we can start to get into this area of therapeutic monitoring.
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Stephen Fodor talks about bringing the knowledge gathered by the Human Genome Project to the individual researcher.
Pat Brown talks about using microarrays to discover the differences between cancer cells and healthy cells.
Stephen Fodor talks about the need to look broadly across the genome to find the relationship between genes and health in different people.
Stephen Fodor discusses the experiments that laid the groundwork for GeneChip technology.
Stephen Fodor continues his discussion of the experiments that laid the groundwork for GeneChip technology.
David Botstein discusses how identifying the molecular mechanisms of cancer will lead to the development of improved therapies.
Stephen Fodor personalized medicine.
David Botstein talks about the goal of using microarray analysis to improve cancer diagnosis.
David Botstein (sitting with Pat Brown) talks about how innovations in genomics might lead to personalized medicine.
Denise talks about her family's affliction with inherited breast cancer and her decision to have her breasts removed as a preventive measure.