Family affliction, Denise
Interviewee: Denise. Denise talks about her family's affliction with inherited breast cancer and her decision to have her breasts removed as a preventive measure. (DNAi Location: Applications > Genes and medicine > Gene testing > Denise > Decision to have her breasts removed)
Well my mom was diagnosed with breast cancer in 1978 and then my aunt a couple of years following that was diagnosed with breast cancer. And then my cousin Renee was diagnosed with breast cancer also, and then my other cousin Audrey was diagnosed with breast cancer. And my sister had just been diagnosed with breast cancer and so I had decided that I needed to do something very quickly, I needed to have my breasts removed, that seemed to be all the doctors', you know, consensus also.
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Barbara Weber talks about how she had discovered information that could be useful to families afflicted with hereditary breast cancer even before the gene was found.
BRCA1, on chromosome 17, is one of the genes associated with hereditary breast cancer.
BRCA2, on chromosome 13, is one of the genes associated with hereditary breast cancer
Mary-Claire King talks about her first steps toward finding the gene responsible for certain kinds of inherited breast cancer.
Mark Skolnick talks about forming a company to discover genes and develop genetic tests.
Matt Ridley talks about chromosome 13, BRCA2 gene for breast cancer susceptibility.
Mary-Claire King talks about the value of using the centuries-old tool of family pedigrees to gain insight into patterns of inheritance of genetic disorders.
Denise talks about learning about DNA, and deciding if she wanted to know if she was at increased risk for breast cancer.
Mary-Claire King reflects on how knowledge gained from the identification of BRCA1 and BRCA2 could lead to improved cancer treatments.
Pat Brown talks about using microarrays to discover the differences between cancer cells and healthy cells.