What is breast cancer?
BRCA1, on chromosome 17, is one of the genes associated with hereditary breast cancer. Although gender, age and environmental effects are major risk factors for breast cancer, having a mutation in either the BRCA1 gene or BRCA2 gene (on chromosome 13) increases the risk.
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- ID: 15938
- Source: DNALC.DNAi
15939. What is breast cancer?
BRCA2, on chromosome 13, is one of the genes associated with hereditary breast cancer
15408. Chromosome 13: BRCA2 gene for breast cancer susceptibility, Matt Ridley
Matt Ridley talks about chromosome 13, BRCA2 gene for breast cancer susceptibility.
15123. Testing for mutations in BRCA1, Mary-Claire King
Mary-Claire King talks about testing for breast cancer.
15118. What to look for in the hunt for BRCA1, Mary-Claire King
Mary-Claire King talks about her first steps toward finding the gene responsible for certain kinds of inherited breast cancer.
15126. Using pedigress in the hunt for BRCA1, Mary-Claire King
Mary-Claire King talks about the value of using the centuries-old tool of family pedigrees to gain insight into patterns of inheritance of genetic disorders.
15124. Better treatment for breast cancer, Mary-Claire King
Mary-Claire King reflects on how knowledge gained from the identification of BRCA1 and BRCA2 could lead to improved cancer treatments.
15079. Family affliction, Denise
Denise talks about her family's affliction with inherited breast cancer and her decision to have her breasts removed as a preventive measure.
15121. Little known in the 1970s about the causes of cancer, Mary-Claire King
Mary-Claire King speaks about how much was yet to be understood about the genetic mechanisms of cancer when she began her hunt for genes associated with breast cancer.
15704. Gene markers on chromosomes
By 1990, King had found a "landmark" that helped her fix the gene's position on a chromosome. This DNA marker was on chromosome 17, and was linked to breast cancer in a subset of the families she studied. She teamed up with Francis Collins in a race to f
16055. Mary-Claire King
MARY-CLAIRE KING (1946- )