Why he formed Myriad, Mark Skolnick
Interviewee: Mark Skolnick. Mark Skolnick talks about forming a company to discover genes and develop genetic tests. (DNAi Location: Applications > Genes and medicine > Gene hunting > Mark Skolnick > Forming Myriad)
So I came up with the idea of using a industrial answer to the question, so we created Myriad, myself and Peter Meldrum, specifically with the goal of isolating the breast cancer susceptibility gene, believing that we then as a company could serve a great social purpose of bringing a diagnostic test, an extremely high quality commercial level diagnostic test, and the education that's required to change doctors' practices, to the world if we were able to discover that gene. And we in fact were able to convince investors that we had a reasonable chance of finding that gene, or other genes if we lost that race, given the resources that I had developed here in Utah.
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Mark Skolnick is Chief Scientific Officer at Myriad Genetics, Inc.
Denise talks about her family's affliction with inherited breast cancer and her decision to have her breasts removed as a preventive measure.
Mark Skolnick talks about taking advantage of the well-documented genealogy of the Mormon pioneers to study inherited genetic disorders.
Genetic testing changed Denise's life.
Matt Ridley talks about chromosome 13, BRCA2 gene for breast cancer susceptibility.
Barbara Weber talks about how she had discovered information that could be useful to families afflicted with hereditary breast cancer even before the gene was found.
Mark Skolnick talks about the hunt for BRCA1.
Mark Skolnick talks about moving on after the discovery of BRCA1 to find and clone another gene associated with breast cancer, BRCA2.
Mary-Claire King talks about testing for breast cancer.
Mary-Claire King speaks about how much was yet to be understood about the genetic mechanisms of cancer when she began her hunt for genes associated with breast cancer.