Delivering the news, Barbara Weber
Interviewee: Barbara Weber. Barbara Weber talks about delivering the news.
And I said "well as you might expect, Vicki, since you have breast cancer you do have the markers that suggest that you have the gene. But Denise you don't, it looks like you don't have what it is that's in your family." And everyone just starts to cry you know, Vicki was crying and Denise was crying and you know everybody was just crying it was just ... it was just amazing it was all things sort of all wrapped up together that I couldn't believe that this had happened at a time when we never really ... we were just thinking about finding the gene you know we weren't thinking about this kind of drama. And they weren't thinking that they were gonna get anytime anything like that anytime soon.
breast cancer gene,barbara weber,breast cancer,gene testing,genetic markers,pedigree
Barbara Weber shows how information from her study on genetic markers associated with inherited breast cancer indicated which family members were at increased risk and which were not.
Genetic testing changed Denise's life.
Barbara Weber talks about how she had discovered information that could be useful to families afflicted with hereditary breast cancer even before the gene was found.
Barbara Weber talks about the dramatic moment when she realized she had information that could change the life of her patient's sister.
Pedigrees are valuable tools in the study of disease inheritance.
Barbara Weber discusses how information from the pedigrees she used in her studies could show which family members were at increased risk for cancer.
Denise talks about the emotional moment when she found out she had been spared the "family curse."
Denise talks about learning about DNA, and deciding if she wanted to know if she was at increased risk for breast cancer.
Denise talks about her family's affliction with inherited breast cancer and her decision to have her breasts removed as a preventive measure.
BRCA1, on chromosome 17, is one of the genes associated with hereditary breast cancer.