Professor Graham Collingridge describes the process of long-term depression (LTD), a way of decreasing the efficiency of synaptic transmission.
LTD is the converse of LTP, which basically means that it is a way of decreasing the efficiency of synaptic transmission. This could be used to reverse the LTP, if you like, to forget the information. Or, it could be used to encode different sorts of information.
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Professor Graham Collingridge describes the process of long-term potentiation (LTP) - the process by which synapses increase their efficiency.
Professor Graham Collingridge describes the roles played by NMDA and AMPA receptors in long-term potentiation (LTP).
Professor Graham Collingridge briefly describes how the NMDA receptor facilitates Hebbian learning (a mechanism of synaptic plasticity).
Professor Graham Collingridge describes the glutamate receptor, AMPA, the workhorse receptor for communicating information.
Professor Tom O'Dell discusses synaptic plasticity - the strengthening and weakening of synaptic connections between neurons.
Professor Graham Collingridge explains that synaptic plasticity is the way most information is stored in the central nervous system.
Professor Seth Grant discusses the complicated relationship between long-term potentiation and learning/memory.
Professor Seth Grant explains that long-term potentiation is based on the principle that synapses become stronger with experience.
Professor Dennis Selkoe discusses the finding that amyloid beta seems to decrease the uptake of glutamate by synapses.
Long-term Potentiation of synaptic transmission is commonly referred to as LTP. It can be recorded in many parts of the nervous system, but is very widely studied in the hippocampus.