Cholinergic hypothesis of Alzheimer’s disease
Professor Donna Wilcock dscusses the cholinergic hypothesis of Alzheimer's disease, which focuses on cholinergic neurons. The hypothesis has not been supported.
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2175. Alzheimer's disease medications - Aricept
Professor Donna Wilcock explains that Aricept can only provide short-term benefit in treating Alzheimer's disease.
2227. Alzheimer's disease
An overview of Alzheimer's disease-related content on Genes to Cognition Online.
2188. Early-onset Alzheimer's disease, 30-65
Professor Donna Wilcock discusses early-onset Alzheimer's disease, which can reach an advanced stage by the age of 50 or 60 years.
2172. Amyloid plaques
Professor Donna Wilcock describes amyloid plaques as clumps of protein in the brain that are one of the three hallmarks of Alzheimer's disease.
2189. Late-onset Alzheimer's disease
Professor Donna Wilcock discusses late-onset Alzheimer's disease, which involves the clearance and/or production of the amyloid beta protein.
2174. Neuron loss
Professor Donna Wilcock describes how neurofibrillary tangles choke neurons, causing them to die. This is one of three hallmarks of Alzheimer's disease.
794. Background to Alzheimer's Disease
Alzheimer’s disease is a progressive brain disorder that causes a gradual and irreversible loss of higher brain functions, including memory, language skills, and perception of time and space,
2035. Acetylcholine and Alzheimer's disease
Professor Kenneth Kosik discusses the biochemistry of Alzheimer's disease in relation to acetylcholine and cholinergic deficiency.
2182. Alzheimer's disease therapy - clinical trials
Professor Donna Wilcock discusses the process of going from a mouse model to human trials for testing the amyloid beta immunization for Alzheimer's disease.
2183. Alzheimer's disease statistics - prevalence and age
Professor Donna Wilcock discusses Alzheimer's disease in the light of increasing prevalence as the population ages.