Early-onset Alzheimer's disease, 30-65
Professor Donna Wilcock discusses early-onset Alzheimer's disease, which can reach an advanced stage by the age of 50 or 60 years.
There are several different types. Early-onset familial Alzheimerâ€™s disease is typically caused by genetic mutations that we can follow through families. These genetic mutations, for the most part, increase the production of amyloid beta in the brain. These patients, typically by 50 or 60 have reasonably advanced Alzheimerâ€™s disease.
alzheimer, familial, early, onset, gene, age, 30, 40, 50, 60, 65, donna, wilcock
- ID: 2188
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2227. Alzheimer's disease
An overview of Alzheimer's disease-related content on Genes to Cognition Online.
2189. Late-onset Alzheimer's disease
Professor Donna Wilcock discusses late-onset Alzheimer's disease, which involves the clearance and/or production of the amyloid beta protein.
794. Background to Alzheimer's Disease
Alzheimer’s disease is a progressive brain disorder that causes a gradual and irreversible loss of higher brain functions, including memory, language skills, and perception of time and space,
2183. Alzheimer's disease statistics - prevalence and age
Professor Donna Wilcock discusses Alzheimer's disease in the light of increasing prevalence as the population ages.
2027. Alzheimer’s disease - early onset
Professor Kenneth Kosik discusses early-onset Alzheimer's disease, which affects 1% of all people with the disease.
2190. Late-onset genes for Alzheimer's disease
Professor Donna Wilcock discusses the late-onset gene for Alzheimer's disease, ApoE4, which increases the risk of developing the disease.
2172. Amyloid plaques
Professor Donna Wilcock describes amyloid plaques as clumps of protein in the brain that are one of the three hallmarks of Alzheimer's disease.
2177. Cholinergic hypothesis of Alzheimer’s disease
Professor Donna Wilcock dscusses the cholinergic hypothesis of Alzheimer's disease, which focuses on cholinergic neurons. The hypothesis has not been supported.
2005. Alzheimer's - closing in on early diagnosis
Doctor Thomas Insel discusses recent findings of structural changes in the brains of teenagers may be warning signs for the potential onset of Alzheimer's disease.
2137. Amyloid plaques - rarely found in childhood
Professor Dennis Selkoe discusses the age at which plaque-forming a-beta can begin to build up. Children with Down syndrome may have these plaques, otherwise childhood instances are rare.