The other codons: Nirenberg and the genetic code
After the easy codons, exact triplets had to be made in order to finish deciphering the rest. Marshall Nirenberg and a group of scientists including Maxine Singer, Marianne Grunberg-Manago, Phil Leder were involved in this process. Har Gobind Khorana also worked on this problem.
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- ID: 15883
- Source: DNALC.DNAi
Marshall Nirenberg, National Institute of Health, 1960.
Marshall Nirenberg talks about the contributions of Maxine Singer, Marianne Grunberg-Monago and Phil Leder.
Several researchers crack the genetic code.
Marshall Nirenberg, Har Gobind Khorana, and Robert Holley shared the 1968 Nobel Prize for Physiology and Medicine. Nirenberg and Khorana cracked the genetic code. Holley sequenced and deduced the structure of the first tRNA molecule.
Marshall Nirenberg talks about Gobind Khorana, who synthesized many of the triplets needed to finish the decoding process.
After decoding the "easy" codons, Marshall Nirenberg talks about his strategy for decoding the rest.
1966 Cold Spring Harbor Symposium on protein synthesis. (L-R) Har Gobind Khorana, Francis Crick, Marianne Grunberg-Manago.
Using charged tRNAs to prove triplet nature of the genetic code, and to determine the base sequences of codons
Asilomar meeting. February 1975. (L to R) Maxine Singer, Norton Zinder, Sydney Brenner, Paul Berg.
Har Gobind Khorana, Marshall Nirenberg, and Robert Holley shared the 1968 Nobel Prize for Physiology and Medicine. Nirenberg and Khorana cracked the genetic code. Holley sequenced and deduced the structure of the first tRNA molecule.