Many Genes for Bipolar Disorder
Doctor Ellen Leibenluft explains that there is no one gene for bipolar disorder. Instead, what we have what are called genes of small effect.
The one thing that we know most clearly about the genetics of bipolar disorder is that itâ€™s complex. There is no one gene for bipolar disorder. Instead, what we have what are called genes of small effect. We know that there are a number of different genes which are likely to work together in some way to cause bipolar disorder. There's a great deal of research going on with this right now and for the first time we're starting to have studies that are very, very large. When youâ€™ve got these genes of small effect it's important that you have samples that are very large, and it's only now that people are starting to amass those kinds of samples. So hopefully in the near future we'll be learning a lot more about the genetic architecture of bipolar disorder, but we do know that it will be very complicated.
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Doctor Ellen Leibenluft discusses the similarities between schizophrenia and bipolar disorder, which have some genetic risk factors in common.
Doctor Ellen Leibenluft explains that although individuals with bipolar disorder can have trouble interpreting emotional expressions, this is much more subtle than in autism.
Doctor Anil Malhotra discusses the search for genes in both bipolar disorder and schizophrenia, both of which are in their infancy.
Doctor Ellen Lebienluft explains how brain imaging data is being combined with genetic research to understand how bipolar disorder affects brain function.
Doctor Ellen Leibenluft discusses biochemical treatments for biploar disorder, including pescriptions of lithium and Valproate, which target second-messenger systems.
Doctor Ellen Leibenluft explains that women and men are equally likely to develop bipolar disorder. Women are, however, more likely to develop the disorder after giving birth.
An overview of bipolar disorder-related content on Genes to Cognition Online.
Doctor Ellen Liebenluft explains that individuals with bipolar disorder can spend some time in a normal mood, which is called euthymia.
Doctor Ellen Leibenluft discusses brain regions associated with bipolar disorder, including the amygdala (which may be smaller) and prefrontal cortex (which may have different activity).
Professor Pat Levitt discusses that although it shares genes with other disorders, schizophrenia is likely caused by unique combinations of genes.