In the early 1990s, Stephen Fodor and his team developed a technique to produce miniature arrays of biological molecules. Their work led to the first DNA chip, and became the basis of techniques for large-scale genomic studies. The company Affymetrix was spun off in the early 1990s to focus on DNA GeneChipâ„¢
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- ID: 15919
- Source: DNALC.DNAi
Stephen Fodor is Chairman and CEO of Affymetrix, Inc
Steve Fodor changed the way genomes can be screened with GeneChipsÂ®.
GeneChips® are the basis for large-scale genomic studies that analyze the action of tens of thousands of genes at once.
Stephen Fodor talks about bringing the knowledge gathered by the Human Genome Project to the individual researcher.
Stephen Fodor talks about the photolithographic technique used to synthesize pieces of DNA on the surface of GeneChipsÂ®.
Stephen Fodor continues his discussion of the experiments that laid the groundwork for GeneChip technology.
Stephen Fodor discusses the experiments that laid the groundwork for GeneChip technology.
The last step! A technician applies the label and serial number to a GeneChip cassette. The GeneChip is now ready to be used in a laboratory to perform large-scale genetic analysis.
Affymetrix, the makers of GeneChip arrays.
Igor Dawid and Thomas Sargent explain how they developed subtractive mRNA hybrization to find genes expressed by different cell types. Pat Brown and Steve Fodor show how genomes can be screened with DNA arrays and GeneChips™