Transcription/translation - Promoters
Promoters are DNA sequences located in the 5' region adjacent to the transcriptional start site. RNA polymerase and accessory proteins (transcription factors) bind to the promoter to initiate production of an mRNA transcript. Interactions of proteins at the promoter regulate gene actvity by activating or repressing transcription.
- ID: 15547
- Source: DNALC.DNAi
15546. Transcription/translation - Untranslated regions
15549. Transcription/translation - Exons and introns
In most eukaryotic genes, coding regions (exons) are interrupted by noncoding regions (introns).
15579. Transcription and translation
An image relating transcription and translation.
15550. Transcription/translation -PolyA-tails - the end
The majority of eukaryotic mRNAs contain a tract of A residues at the end. These polyA-tails are not encoded in the DNA. Rather, they are added to the pre-mRNA "post-transcriptionally" (after transcription). The end of pre-mRNA is cut by a specific enzyme
15545. Tanscription/translation - Start and stop codons
The diagram represents a single strand of DNA containing a gene, in purple. Remember this gene is "read" in the 5' to 3' direction to produce an mRNA.
2299. Transcription Factors Can Turn Genes On and Off
Doctor Anil Malhotra discusses how transcription factors can turn genes on or off, possibly leading to increased or reduced risk of illness.
2051. Gene expression - different levels in different cells
Professor Rusty Lansford explains that all genes are not expressed in the same levels in different cells; there is a lot of differential regulation.
15473. The Central Dogma: transcription and translation, James Watson
James Watson talks about the Central Dogma: transcription and translation.
1180. Cortical Asymmetry - Left Brain, Right Brain
Professor Daniel Geschwind explains that cortical asymmetry refers to differences between the right and left side of the brain. This relates to gene expression.
16528. Concept 24: The RNA message is sometimes edited.
RNA splicing removes non-coding introns and splices together exons.