Analyzing human DNA variations, Kenneth Kidd
Interviewee: Kenneth Kidd. Analyzing human DNA variations.
We look at DNA of humans, and of modern humans, not of ancient ones. We collect blood samples from normal, healthy living people from different populations around the world. And look at the DNA sequence, usually not sequenced strictly, but at variants that we know about and type those variants so we know for that limited bit of DNA what flavor, what allele each individual has.
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Kenneth Kidd talks about frequency of different DNA variations.
Variation between mtDNA (HVR1) samples from chimp, Neandertal and human.
Alec Jeffreys talks about can DNA variations be detected.
A DNA fingerprint is a profile of a person's inherited DNA variations, specifically repeated sequences
An image of a DNA sequencer.
Stephen Fodor talks about limit to the gene chip.
Human mitochondrial DNA is 16,569 base pairs in length.
When comparing Neandertal and human mtDNA, researchers found that the differences between the sequences put Neandertals outside the range of variation of modern humans.
Mitochondrial genome sequences humans populations modern MRCA most recent common ancestor ancestry relationships phylogenetic trees mtDNA Macaulay.
Mitochondrial DNA research pioneer Douglas Wallace speaks about the populations he samples and the direct application of the research.