A mitochondrial DNA sequence

The DNA found in mitochondria, the energy-producing organelles of cells, is often analyzed to trace evolutionary pathways. Mitochondrial DNA (mtDNA) has a high "substitution" or mutation rate, compared with other sites in our genome. mtDNA is transmitted only from mother to child, and can be inherited intact over thousands of generations. Mutations in the mtDNA sequence can be used to reconstruct the maternal lineage of populations.

mtdna sequence,organelles of cells,maternal lineage,mutation rate,mitochondrial dna,dna sequence,mutations,pathways,populations,generations

  • ID: 15979
  • Source: DNALC.DNAi

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15978. Mitochondrial DNA: a closer look

DNA found in the mitochondrion of a cell differs in structure and is separate from the DNA found in the cell nucleus. Mitochondrial DNA, or mtDNA, exists as a circular loop of double-stranded DNA rather than the linear form found in nuclear DNA. However,

  • ID: 15978
  • Source: DNAi

15977. Maternal inheritance

Unlike nuclear DNA, mtDNA is  inherited solely from the mother. (Mitochondria are predominantly from the mother’s egg and not from the father’s sperm.) Therefore, mtDNA sequences or orders of nucleotides generally remain constant over many generation

  • ID: 15977
  • Source: DNAi

15418. Mitochondrial DNA, Matt Ridley

Matt Ridley talks about Mitochondrial DNA.

  • ID: 15418
  • Source: DNAi

15178. Mitochondrial DNA and the molecular clock, Douglas Wallace

Geneticist Douglas Wallace explains a method of mapping a population's history using the mutations accumulated by its members.

  • ID: 15178
  • Source: DNAi

16655. Higher cells incorporate an ancient chromosome.

DNAFTB Problem 30: Trace mitochondria through Queen Victoria's decendants and solve the mystery of the Romanovs.

  • ID: 16655
  • Source: DNALC.DNAFTB

15975. Human and mtDNA variation

When comparing Neandertal and human mtDNA, researchers found that the differences between the sequences put Neandertals outside the range of variation of modern humans.

  • ID: 15975
  • Source: DNAi

15976. Neandertal and human (mtDNA)

When comparing Neandertal and human mtDNA, researchers found that the differences between the sequences put Neandertals outside the range of variation of modern humans.

  • ID: 15976
  • Source: DNAi

15980. Accumulating mutations

Mutations are the grist of evolution, and have accumulated in our DNA over time. When populations separate, each group accumulates their own unique set of DNA mutations.

  • ID: 15980
  • Source: DNAi

15611. mtDNA / Y chromosome pedigree, animated image

A pedigree illustrating maternal inheritance of mtDNA and paternal inheritance of the Y chromosome.

  • ID: 15611
  • Source: DNAi

16088. mtDNA tree all humans; Macaulay

Mitochondrial genome sequences humans populations modern MRCA most recent common ancestor ancestry relationships phylogenetic trees mtDNA Macaulay.

  • ID: 16088
  • Source: DNAi