What are Model Systems? (2)
Professor David Van Vactor explains that model systems are simple organisms that allow us to study and manipulate gene function and development.
Model systems are simple organisms that share a common design principle with our more complex human, mammalian, vertebrate body plan and molecular mechanism. But they’re very accessible to manipulation, to really understand fundamental mechanisms of cellular function, development, and are often a very helpful way to explore questions in greater detail.
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Professor David Van Vactor provides a simple explanation for why researchers work with model systems (model organisms).
Professor David Van Vactor discusses the properties that make the fruit fly (drosophila) a powerful model system.
Professor David Van Vactor describes how axons grow during neurodevelopment.
Professor David Van Vactor explains how growth cones guide axons during neurodevelopment.
Professor David Van Vactor describes the role of receptor molecules, which receive signals from outside the cell, passing the signal to the inside.
Professor David Van Vactor discusses how growth cones read molecular 'signposts,' which help axons find the correct path.
Model organisms share with humans many key biochemical and physiological functions that have been conserved (maintained) by evolution.
Professor David Van Vactor discusses what happens during neurodevelopment when an axon reaches its final destination.
Professor David Van Vactor describes the structure of the cytoskeleton, which acts as a scaffold for the cell.
Dr. Nicole King and Dr. Seth Grant join Cold Spring Harbor Laboratory's David Micklos to discuss the evolution of complex, multicellular animals. Remarkably, the molecules that have driven brain evolution, are the same molecules found in simple unicellula