What are Model Systems? (1)
Professor David Van Vactor provides a simple explanation for why researchers work with model systems (model organisms).
Model systems are convenient organisms that provide us with a very facile way of approaching detailed biologic questions - sharing many of the same attributes of our own biology, but yet amenable open to manipulations that we can’t really perform with humans.
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Professor David Van Vactor explains that model systems are simple organisms that allow us to study and manipulate gene function and development.
Professor David Van Vactor discusses the properties that make the fruit fly (drosophila) a powerful model system.
Professor David Van Vactor describes how axons grow during neurodevelopment.
Professor David Van Vactor explains how growth cones guide axons during neurodevelopment.
Professor David Van Vactor discusses what happens during neurodevelopment when an axon reaches its final destination.
A human is a complicated organism, and it is considered unethical to do many kinds of experiments on human subjects. For these reasons, biologists often use simpler “model” organisms that are easy to keep and manipulate in the laboratory.
Professor David Van Vactor discusses how growth cones read molecular 'signposts,' which help axons find the correct path.
Professor David Van Vactor describes the structure of the cytoskeleton, which acts as a scaffold for the cell.
Professor David Van Vactor describes the role of receptor molecules, which receive signals from outside the cell, passing the signal to the inside.
Doctor Josh Dubnau explains that model systems are particular species of animals that substitute for humans or other animals. For genetic and historic reasons, the fruit fly is a commonly used model.