Growth Cones (3)
Professor David Van Vactor discusses what happens during neurodevelopment when an axon reaches its final destination.
So, when a growth cone reaches its final destination, the neuron faces a need to change from an exploratory mode, to find its partner, to a new mode in which it will create functional active synaptic connections. In some cases the growth cone itself will transform from a motile exploratory apparatus into a stable connection, a synaptic partner.
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Professor David Van Vactor explains how growth cones guide axons during neurodevelopment.
Professor David Van Vactor discusses how growth cones read molecular 'signposts,' which help axons find the correct path.
Professor David Van Vactor describes how axons grow during neurodevelopment.
Professor David Van Vactor provides a simple explanation for why researchers work with model systems (model organisms).
Professor David Van Vactor discusses the properties that make the fruit fly (drosophila) a powerful model system.
Professor David Van Vactor explains that model systems are simple organisms that allow us to study and manipulate gene function and development.
Professor David Van Vactor describes the structure of the cytoskeleton, which acts as a scaffold for the cell.
Professor David Van Vactor describes the role of receptor molecules, which receive signals from outside the cell, passing the signal to the inside.
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells.
Professor Pat Levitt likens the brain to a rosebush, where the developing nervous system needs pruning and maintenance to function optimally.