Growth Cones (1)
Professor David Van Vactor explains how growth cones guide axons during neurodevelopment.
So, the growth cone is a fascinating structure at the tip of the developing axon discovered over one hundred years ago by a great Spanish anatomist, Cajal. And it is a very dynamic structure, almost like a tiny hand at the tip of the axon, which explores the embryonic landscape. It is the growth cone that does most of the work of navigation to reach targets in the developing nervous system.
neurodevelopment, axon, growth, cones, guidance, cajal, david, van, vactor,
Professor David Van Vactor discusses how growth cones read molecular 'signposts,' which help axons find the correct path.
Professor David Van Vactor discusses what happens during neurodevelopment when an axon reaches its final destination.
Professor David Van Vactor describes how axons grow during neurodevelopment.
Professor David Van Vactor provides a simple explanation for why researchers work with model systems (model organisms).
Professor David Van Vactor discusses the properties that make the fruit fly (drosophila) a powerful model system.
Professor David Van Vactor explains that model systems are simple organisms that allow us to study and manipulate gene function and development.
Professor David Van Vactor describes the structure of the cytoskeleton, which acts as a scaffold for the cell.
Professor David Van Vactor describes the role of receptor molecules, which receive signals from outside the cell, passing the signal to the inside.
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells.
Professor Pat Levitt likens the brain to a rosebush, where the developing nervous system needs pruning and maintenance to function optimally.