Biology & 3D Animation Library

GeneChip®

In the early 1990s, Stephen Fodor and his team developed a technique to produce miniature arrays of biological molecules. Their work led to the first DNA chip, and became the basis of techniques for large-scale genomic studies. The company Affymetrix was spun off in the early 1990s to focus on DNA GeneChip®.

This animation is also available as INTERACTIVE MEDIA .

In the early 1990s, Stephen Fodor and his team developed a technique to produce miniature arrays of biological molecules. Their work led to the first DNA chip, and became the basis of techniques for large-scale genomic studies. The company Affymetrix was spun off in the early 1990s to focus on DNA GeneChips®.

Stephen Fodor,dna chip,biological molecules,genechip,affymetrix,arrays,early 1990s,large scale

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16757. Biography 36: Stephen P. A. Fodor (1953- )

Steve Fodor changed the way genomes can be screened with GeneChips®.

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15993. GeneChips®

GeneChips® are the basis for large-scale genomic studies that analyze the action of tens of thousands of genes at once.

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Stephen Fodor talks about bringing the knowledge gathered by the Human Genome Project to the individual researcher.

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15083. Making DNA chips, Stephen Fodor

Stephen Fodor talks about the photolithographic technique used to synthesize pieces of DNA on the surface of GeneChips®.

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15051. How GeneChip™ was developed (Part II), Stephen Fodor

Stephen Fodor continues his discussion of the experiments that laid the groundwork for GeneChip™ technology.

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15050. How GeneChip™ was developed (Part I), Stephen Fodor

Stephen Fodor discusses the experiments that laid the groundwork for GeneChip™ technology.

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15670. Making GeneChips® at Affymetrix

The last step! A technician applies the label and serial number to a GeneChip cassette. The GeneChip is now ready to be used in a laboratory to perform large-scale genetic analysis.

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15661. Making GeneChips™ at Affymetrix

Affymetrix, the makers of GeneChip™ arrays.

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16736. Animation 36: Different genes are active in different kinds of cells.

Igor Dawid and Thomas Sargent explain how they developed subtractive mRNA hybrization to find genes expressed by different cell types. Pat Brown and Steve Fodor show how genomes can be screened with DNA arrays and GeneChips™

  • ID: 16736
  • Source: DNALC.DNAFTB