Neurotransmitters Systems Work Together
Doctor Ellen Leibenluft explains that neurotransmitters and neuromodulators in the brain are heavily inter-connected and work together as a system.
One important thing to understand in the brain is that to a certain extent itâ€™s all about communication. Itâ€™s all about communication between neurons and between brain regions, and thatâ€™s why thereâ€™s been increased recent interest in not just brain regions that might be involved in bipolar disorder but brain circuits. So functionally, whatâ€™s the communication thatâ€™s going on for example between the amygdala and the ventral prefrontal cortex? Or between the amygdala and parts of the brain that processes emotional stimuli such as faces? In the same way, thereâ€™s increased appreciation that these various neurotransmitter systems, neuromodulator systems, work together. So dopamine and serotonin, for example, interact with each other and influence each other's levels, so a lot of this has to do with putting together a very complex system and understanding how both different brain regions and different brain chemicals work together to create the symptoms that we ultimately see.
Bipolar, disorder, neurotransmitter, biochemical, biochemistry, communication, network, amygdala, ellen, leibenluft
Doctor Ellen Leibenluft discusses some of the biochemicals that have been associated with bipolar disorder, including dopamine, serotonin, and glutamate.
Doctor Ellen Leibenluft discusses biochemical treatments for biploar disorder, including pescriptions of lithium and Valproate, which target second-messenger systems.
An overview of bipolar disorder-related content on Genes to Cognition Online.
Doctor Ellen Leibenluft discusses brain regions associated with bipolar disorder, including the amygdala (which may be smaller) and prefrontal cortex (which may have different activity).
Doctor Ellen Leibenluft explains that women and men are equally likely to develop bipolar disorder. Women are, however, more likely to develop the disorder after giving birth.
Doctor Ellen Liebenluft explains that individuals with bipolar disorder can spend some time in a normal mood, which is called euthymia.
Doctor Ellen Leibenluft explains that although individuals with bipolar disorder can have trouble interpreting emotional expressions, this is much more subtle than in autism.
Doctor Ellen Leibenluft explains that there is no one gene for bipolar disorder. Instead, what we have what are called genes of small effect.
Doctor Ellen Leibenluft discusses the similarities between schizophrenia and bipolar disorder, which have some genetic risk factors in common.
Doctor Ellen Leibenluft discusses possible reasons for the dramatic increase in the rates of diagnosis in childhood bipolar disorder in the past decade.