The Brain Rewad System - Brain Structures
Doctor Abraham Zangen discusses the key structures underlying the brain reward system, a complex neural network that includes the nucleus accumbens and hippocampus.
So the hippocampus is part of the limbic system. It is more associated with memory function and spatial memory and long-term memory. However, there is interaction between the hippocampus and the nucleus accumbens by glutamatergic neurons that project from the ventral subiculum (a subregion of the hippocampus) to the nucleus accumbens and was shown to have a critical role in reward functions. The brain reward system is very complex, I mean it is not just one region in the brain â€“ the nucleus accumbens â€“ it is the whole network. The projection coming from the hippocampus to the accumbens appears to be very important in reward function.
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Professor Trevor Robbins explains that the dopamine system is a group of cells originating in the midbrain whose function may be to prepare the brain to think, move, and anticipate rewards.
Doctor Larry Young discusses how vasopressin and oxytocin contribute to the reward system, which can promote behavior such as bonding and drug addiction.
Doctor Abraham Zangen discusses how transcranial magnetic stimulation (TMS) can stimulate different areas of the brain and treat depression.
Professor Trevor Robbins explains that the reward system, where dopamine mediates messages to the nucleus accumbens, is artificially activated by certain drugs.
Doctor Abraham Zangen discusses a treatment developed by his group that uses transcranial magnetic stimulation (TMS) to treat depression.
The hippocampus is closely aligned to memory formation. It is an important early storage place for long–term memory, and is involved in the transition to more enduring permanent memory.
The idea that drug addiction is a result of 'learning gone wild' was bolstered by several reports.
The potential gains of improving or therapeutically altering memory are compelling, but ethical considerations are imperative.
The basal ganglia, a group of interconnected brain areas located deep in the cerebral cortex, have proved to be at work in learning, the formation of good and bad habits, and some psychiatric and addictive disorders.
Doctor Abraham Zangen point out that dopamine and BDNF levels in the nucleus accumbens and hippocampus of depressed patients are different. Treatment with antidepressants or ECT can impact these differences.