Dopamine and Reward
Professor Trevor Robbins explains that the reward system, where dopamine mediates messages to the nucleus accumbens, is artificially activated by certain drugs.
So the concept of the reward system is a part of the brain where natural rewards, like food and water, maybe sex, exert their effects to change behavior. These effects are thought to occur via the activity of the dopaminergic, the dopamine neurotransmitter system, sending its messages to the nucleus accumbens, this structure in the base of the forebrain. It is commonly thought that drugs of abuse hijack this system. They short-circuit the system by producing some of the rewarding effects that natural rewards normally produce, but without their other aspects. So, this probably is a bad thing because the other sensory qualities of the rewards are not there. But that in general is what we mean by reward system.
reward, system, dopamine, nucleus, accumbens, brain, drug, addiction, abuse, trevor, robbins,
- ID: 1146
- Source: DNALC.G2C
- Download: Theora Video MPEG 4 Video Windows Media Video
Related Content
1145. Drug Addiction - Chemistry and the Brain
Professor Trevor Robbins explains that drug addiction involves chemical and neural processes with dopamine and the nucleus accumbens particularly important.
812. The Dopamine System
Professor Trevor Robbins explains that the dopamine system is a group of cells originating in the midbrain whose function may be to prepare the brain to think, move, and anticipate rewards.
837. Addiction as Overlearning
The idea that drug addiction is a result of 'learning gone wild' was bolstered by several reports.
2383. The Reward System includes Vasopressin and Oxytocin
Doctor Larry Young discusses how vasopressin and oxytocin contribute to the reward system, which can promote behavior such as bonding and drug addiction.
1392. Biochemistry of Depression
Doctor Jon Lieberman discusses three neurotransmitters that have been associated with depression - dopamine, serotonin, and norepinephrine.
1154. Basal Ganglia - Primary Functions
Professor Trevor Robbins discusses the function of a set of structures called the basal ganglia, which seem to be involved in response selection.
2329. The Brain Rewad System - Brain Structures
Doctor Abraham Zangen discusses the key structures underlying the brain reward system, a complex neural network that includes the nucleus accumbens and hippocampus.
1199. ADHD - Noradrenaline and Dopamine
Professor Trevor Robbins discusses ADHD in relation to noradrenaline and dopamine, both of which are enhanced by ADHD medications such as Ritalin.
1149. Noradrenaline (Norepinephrine) and ADHD
Professor Trevor Robbins discusses whether ADHD is a disorder of the noradrenaline system.
2331. Altered BDNF and Dopamine Levels In Depression
Doctor Abraham Zangen point out that dopamine and BDNF levels in the nucleus accumbens and hippocampus of depressed patients are different. Treatment with antidepressants or ECT can impact these differences.