Preventing Alzheimer's disease?
Professor Dennis Selkoe points out that although Alzheimer's disease is primarily a genetic disease, environmental factors may be preventative.
Another factor may be the phenomenon of â€˜use it or lose itâ€™; perhaps if you use your mind, use your brain (which we encourage everyone to do of course) a lot throughout your life, you are less likely to get Alzheimerâ€™s [disease]. But whatâ€™s the chicken and whatâ€™s the egg here? It really is a chicken and egg problem; maybe it is the people who are able to use their minds quite effectively, have challenging occupations and do important things with their brainpower. They already have such a good physiological reserve in the brain that even if they were to get Alzheimerâ€™s disease, they resist its badness, so to speak. Or is it the other way around; is it the cart before the horse, and that is that by training their mind to do a lot of complicated stuff throughout their lives and work in intellectually challenging fields, then they build up their reserves. So we donâ€™t know which one it is. The reserve is there from the beginning at birth or during development and that resists Alzheimerâ€™s [disease], or the person who happens to be interested in doing a lot of work with their mind builds up a resistance, and it might well be both. Although scientists like myself were skeptical of the 'use it or lose it' idea, weâ€™re starting to see some evidence of that in animal work and even in human psychology.
alzheimer, resistance, preventative, environment, environmental, factors, use it or lose it, dennis, selkoe
Professor Dennis Selkoe points out that although Alzheimer's disease is primarily a genetic disease, environmental factors such as exercise may be important.
An overview of Alzheimer's disease-related content on Genes to Cognition Online.
Professor Dennis Selkoe points out that although Alzheimer's disease is primarily a genetic disorder, environmental factors do contribute.
Professor Dennis Selkoe discusses mild cognitive impaitment, a precursor to Alzheimer's disease. Early identification may be critical to treatment.
Professor Daniel Geschwind describes resaerch that shows that keeping the brain active can build up resistance to Alzheimer's disease.
Professor Dennis Selkoe explains that amyloid beta oligomers - small assemblies of amyloid beta protein associated with Alzheimer's disease - do not cause plaques but prevent them.
Professor Dennis Selkoe discusses the degree to which the ApoE4 gene is associated with early onset Alzheimer's disease.
Alzheimer’s disease is a progressive brain disorder that causes a gradual and irreversible loss of higher brain functions, including memory, language skills, and perception of time and space,
Professor Donna Wilcock discusses research that correlates higher education levels with Alzheimer's disease prevention. This finding has not been fully supported.
American Eugenics Party pamphlet detailing their views