Exercise may fight Alzheimer's disease
Professor Dennis Selkoe points out that although Alzheimer's disease is primarily a genetic disease, environmental factors such as exercise may be important.
So what are the environmental factors that could lead to Alzheimer’s [disease]? We think that one of them is exercise. Now every doctor in the world will tell you that exercise is wonderful for almost everything, and there is a lot of truth to that. Alzheimer's [disease], even though it’s not a disease of muscle and movement is no exception. Exercise seems to be associated, even in animal models where we express the amyloid parent protein and watch the amyloid build up in the memory centers of the brain, even there exercise lowers amyloid itself which is quite striking, and several scientists have done that. I haven’t worked on that myself.
alzheimer, environment, environmental, factors, exercise, brain, dennis, selkoe
An overview of Alzheimer's disease-related content on Genes to Cognition Online.
Professor Dennis Selkoe points out that although Alzheimer's disease is primarily a genetic disease, environmental factors may be preventative.
Professor Dennis Selkoe points out that although Alzheimer's disease is primarily a genetic disorder, environmental factors do contribute.
Professor Daniel Geschwind describes resaerch that shows that keeping the brain active can build up resistance to Alzheimer's disease.
Professor Dennis Selkoe concludes that neurons are not the only type of cell affected in Alzheimer's disease.
Professor Dennis Selkoe discusses the degree to which the ApoE4 gene is associated with early onset Alzheimer's disease.
Professor Dennis Selkoe discusses the largely linear relationship between a-beta and cell death in the brain.
Professor Dennis Selkoe discusses the age at which plaque-forming a-beta can begin to build up. Children with Down syndrome may have these plaques, otherwise childhood instances are rare.
Professor Dennis Selkoe discusses an experiment by his group, which found that a-beta oligomers temporarily injected into rats' brains caused temporary forgetfulness.
Professor Kenneth Kosik discusses lifestyle factors that will delay onset of Alzheimer’s disease. These include diet, exercise, controlling hypertension, and not smoking.