Childhood bipolar disorder - brain abnormalities
Professor James Potash discusses the dramatic increase in the rates of diagnosis of childhood bipolar disorder, which has risen forty-fold in recent years.
So about half the people with bipolar [disorder] 1 have the illness before age 21, roughly. Now the issue of childhood onset is a controversial one because the diagnosis of bipolar disorder has increased; if you look at outpatient records in the United States, the diagnosis has increased an amazing forty-fold over the last decade or two. Thatâ€™s a gigantic increase, and presumably a lot of that has to do with increased awareness and recognition of the illness. Another part of it probably has to do with widening diagnostic boundaries; there are a lot of people being called bipolar disorder who donâ€™t meet what I would consider the classic definition.
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Professor James Potash describes how endophenotypes are used to study bipolar disorder. Endophenotypes are essentially subtypes of larger symptoms.
Professor James Potash explains that most individuals with bipolar disorder lead normal lives and respond well to lithium medication.
Professor James Potash discusses studies that show reductions in hippocampal volume in people with depression and abnormalities in cingulate areas in patients with bipolar disorder.
Professor James Potash explains that, for many bipolar disorder patients, managing medications can be difficult.
Professor James Potash discusses evidence from a number of studies that individuals with mood disorders are more likely to be highly creative.
Professor James Potash explains that bipolar disorder is episodic: people get ill, then they get well again and then the illness may come back again at a later date.
An overview of bipolar disorder-related content on Genes to Cognition Online.
Doctor Ellen Leibenluft discusses possible reasons for the dramatic increase in the rates of diagnosis in childhood bipolar disorder in the past decade.
Professor James Potash explains that twin studies dating back to the 1920s have identified bipolar disorder as a genetic disorder.
Professor James Potash discusses two hypotheses on how lithium, which has been successfully used to treat bipolar disorder for many years, may affect the brain.