Roger Kornberg, clip 5
Dr. Kornberg is a Professor of Structural Biology at Stanford University's school of medicine. He did pioneer work on chromatin structure, and is now working on gene regulation and control.
roger kornberg, gene regulation, eukaryotes, mechanism of regulation, transcription, bacteria, blanket repression, selective activation, blanket activity, selective shut down
- ID: 16643
- Source: DNALC.DNAFTB
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In 1974, Roger Kornberg worked out the importance of histones to chromatin structure.
Promoters are DNA sequences located in the 5' region adjacent to the transcriptional start site.
Mechanism of condensation -- accordion vs. ball of yarn.
Early experiences with science.
Packing ratio of DNA.
Hierarchy of levels of chromatin condensation.
Jacques Monod and François Jacob work with how bacteria breaks large sugars into smaller pieces.
The A0439 protein acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases.
The idea that drug addiction is a result of 'learning gone wild' was bolstered by several reports.
CAMP response element-binding protein 2(CREB2) is also known as Activating Transcription Factor 2 (ATF2). CREB2 is a CREB repressor, which means it inhibits long-term memory formation.