Roger Kornberg, clip 3
Dr. Kornberg is a Professor of Structural Biology at Stanford University's school of medicine. He did pioneer work on chromatin structure, and is now working on gene regulation and control.
roger kornberg, structural biology, gene regulation, packing ratio, dna, nucleosome, DNA, helix
- ID: 16641
- Source: DNALC.DNAFTB
- Download: MPEG 4 Video
Mechanism of regulation for prokaryotes vs. eukaryotes.
Mechanism of condensation -- accordion vs. ball of yarn.
Early experiences with science.
Hierarchy of levels of chromatin condensation.
A chromosome is a package for DNA.
DNA is coiled around proteins and packaged as chromatin within the nucleus of cells. Aaron Klug and Roger Kornberg figured out the structure of chromatin. It has been proposed that the coiling (or rather uncoiling) of DNA is a way of controlling the pro
In 1974, Roger Kornberg worked out the importance of histones to chromatin structure.
DNAFTB Problem 29: Test your understanding of chromosome packaging.
DNAFTB Animation 29: Roger Kornberg explains his work with Aaron Klug on histones, which bind DNA to form chromatin.
DNA packaging, 3D animation with sound effects only