Roger Kornberg, clip 2
Dr. Kornberg is a Professor of Structural Biology at Stanford University's school of medicine. He did pioneer work on chromatin structure, and is now working on gene regulation and control.
roger kornberg, hierarchy, structural biology, gene regulation, condensation, medicine, nucleosome, helices, histones, helical
- ID: 16640
- Source: DNALC.DNAFTB
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Mechanism of condensation -- accordion vs. ball of yarn.
Early experiences with science.
Packing ratio of DNA.
Mechanism of regulation for prokaryotes vs. eukaryotes.
In 1974, Roger Kornberg worked out the importance of histones to chromatin structure.
DNAFTB Animation 29: Roger Kornberg explains his work with Aaron Klug on histones, which bind DNA to form chromatin.
Roger Kornberg, 1980s.
An animation showing how histone modifications regulate gene expression
DNA is coiled around proteins and packaged as chromatin within the nucleus of cells. Aaron Klug and Roger Kornberg figured out the structure of chromatin. It has been proposed that the coiling (or rather uncoiling) of DNA is a way of controlling the pro