Biography 26: Stanley Lloyd Miller (1930 - )
Stanley Miller was born in Oakland, California. According to Miller, a scientific career was an easy choice to make since he grew up in the era of scientific discoveries.
Miller graduated from the University of California at Berkeley in 1951 with a Bachelor of Science in chemistry. He then went to the University of Chicago to do graduate work. He attended a seminar Harold Urey gave on the origins of the solar system. Urey presented the idea of organic molecules being synthesized in a primitive Earth atmosphere. When Miller was looking for a thesis project, he remembered this idea and approached Urey. Initially reluctant to put a graduate student on such a risky project, Urey agreed to a six-month trial. Miller designed an apparatus and used it to simulate the conditions on Earth before life appeared. Once the conditions were worked out, Miller quickly got results and synthesized many of the simple organic molecules necessary for life. Miller published his results in Science in 1953; his name was the only one on the paper. Urey did not want his name on the paper as he felt that Miller did all the work.
After graduating in 1954, Miller did a post-doc at the California Institute of Technology. From 1955-1960 he was an assistant professor in the Department of Biochemistry at Columbia University. He then accepted a position in the Department of Chemistry at the University of California, San Diego where he is now a full professor. He has co-authored a book, The Origin of Life on Earth. His research interests focus on pre-biotic synthesis of nucleotides as well as alternative backbones to ribose phosphate in the first genetic material of the pre-RNA world.
Stanley Miller and Harold Urey demonstrated that organic molecules can be synthesized under prebiotic conditions.
primitive earth atmosphere, research interests focus, california institute of technology, origins of the solar system, stanley miller, rna world, lloyd miller, organic molecules, origin of life on earth
- ID: 16584
- Source: DNALC.DNAFTB
Stanley Miller and Harold Urey demonstrate that organic molecules can be synthesized under prebiotic conditions, and Thomas Cech and Sidney Altman show that RNA can have enzymatic activities.
Apparatus used by Stanley Miller in the synthesis of organic molecules.
Harold Urey lecturing to a class in the '50s. It was at a lecture like this that Stanley Miller first heard about the idea of synthesizing organic molecules in a pre-biotic world.
Stanley Miller, 1997.
Marshall Nirenberg, Har Gobind Khorana, and Robert Holley shared the 1968 Nobel Prize for Physiology and Medicine. Nirenberg and Khorana cracked the genetic code. Holley sequenced and deduced the structure of the first tRNA molecule.
Review of Hereditary Genius, The Spectator (11/27/1869) (1)
"Human Sterilization," Human Betterment Foundation (5)
Students will experiment with an interactive animation to compare mutant and wild-type mice in a water maze. They will analyze data and discuss findings of a research paper.
Roy Britten did seminal research on repetitive DNA and its evolutionary origins.
Matthew Meselson and Franklin Stahl invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.