Biography 20: Franklin William Stahl (1929-)

Franklin "Frank" Stahl was born in Boston. He received a B.A. from Harvard University in 1951. Stahl then went to the University of Rochester for graduate work.

While finishing up his Ph.D., Stahl attended a molecular biology course at Woods Hole. The course was being taught by James Watson and Francis Crick, and it was here that Stahl met Matthew Meselson. As they both tell it, during a break in the course, Meselson introduced himself to Stahl who was sitting under a big tree drinking and selling gin and tonics. At the time, Meselson was a graduate student at the California Institute of Technology; he was interested in exploring new methods of experimentation. Stahl had the experience and the math to help Meselson design these experiments. They hit it off right away and made plans for Stahl to do post-doctoral work at Caltech.

In 1957, Stahl and Meselson developed the technique of density gradient centrifugation and used it to prove that DNA was replicated in a semi-conservative way, as predicted by Watson and Crick in their 1953 paper. Meselson and Stahl's paper appeared in 1958.

In 1959, Stahl accepted a position at the University of Oregon where he is now a distinguished professor of Molecular Biology. His current research interest is on the mechanisms of genetic recombination.Franklin "Frank" Stahl was born in Boston. He received a B.A. from Harvard University in 1951. Stahl then went to the University of Rochester for graduate work.

While finishing up his Ph.D., Stahl attended a molecular biology course at Woods Hole. The course was being taught by James Watson and Francis Crick, and it was here that Stahl met Matthew Meselson. As they both tell it, during a break in the course, Meselson introduced himself to Stahl who was sitting under a big tree drinking and selling gin and tonics. At the time, Meselson was a graduate student at the California Institute of Technology; he was interested in exploring new methods of experimentation. Stahl had the experience and the math to help Meselson design these experiments. They hit it off right away and made plans for Stahl to do post-doctoral work at Caltech.

In 1957, Stahl and Meselson developed the technique of density gradient centrifugation and used it to prove that DNA was replicated in a semi-conservative way, as predicted by Watson and Crick in their 1953 paper. Meselson and Stahl's paper appeared in 1958.

In 1959, Stahl accepted a position at the University of Oregon where he is now a distinguished professor of Molecular Biology. His current research interest is on the mechanisms of genetic recombination.

Franklin Stahl and Matthew Meselson invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.

density gradient centrifugation, james watson and francis crick, meselson and stahl, watson and crick, stahl and meselson, matthew meselson, molecular biology course, gin and tonics, francis crick, doctoral work, harvard university

  • ID: 16467
  • Source: DNALC.DNAFTB

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