Meeting Frank Stahl, Matthew Meselson
Interviewee: Matt Meselson. Matt Meselson talks about how he met Frank Stahl, his partner in "the beautiful experiment." Together they proved that DNA is replicated semi-conservatively. (DNAi Location: Code > Copying the code > Players > First meeting with Franklin Stahl)
And one day we were in the brick building, the Lily building with the library in it, on the second or third floor, window was open, and Jim pointed down to a fellow who was sitting across the street underneath a tree on the grass, and said words, I don't remember the exact words, but they were to this effect: that guy thinks he's a hot-shot, let's give him the Hershey Chase Blender experiment to do all by himself in an afternoon, see how good he is. So I thought, this poor guy, and also he sounds like an interesting guy, so after, I don't know what we were doing in that room, planning the course I guess, I went downstairs and introduced myself to this fellow, who was selling gin and tonic. He would buy gin and tonic and ice-cubes, which he got from the lab the ice-cubes, and sell this, and that way he could buy more.
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Franklin Stahl and Matthew Meselson invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
James Watson talks about who he thinks should have won the Nobel Prize in 1962.
Matt Meselson also had a hand in Sydney Brenner's RNA experiment. He talks about the experiment and how they waited for James Watson's group to finished their RNA work before publishing.
Matt Meselson talks about the different models that were considered before their experiment.
Describing his first meeting with James Watson and Matthew Meselson.
Matthew Meselson and Franklin Stahl invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
Matt Meselson talks about how he and Frank were "encouraged" by Max Delbruck to write up the results of their experiment on semi-conservative DNA replication.
Matt Meselson describes the experiment he did with Frank Stahl to prove that DNA is replicated semi-conservatively.
Sydney Brenner talks about James Watson's work on RNA.
More than 25 years after the historic meeting, James Watson looks back.