Video 20: Matthew Meselson, clip 1
Matt Meselson is a Professor in the Department of Molecular and Cellular Biology at Harvard University. His laboratory studies sexual reproduction and genetic recombination, and how and why they are maintained in evolution.
density gradient centrifugation, matthew meselson, molecular and cellular biology, harvard university, sexual reproduction, genetic recombination, laboratory studies, evolution
- ID: 16460
- Source: DNALC.DNAFTB
- Download: MPEG 4 Video
How Meselson came to read the Watson and Crick paper, then think about ways to experimentally test how DNA replicates.
The three models of DNA replication - semi-conservative, conservative, and dispersive - and whether bias played a role in designing/interpreting the experiment.
Matthew Meselson and Franklin Stahl invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
Franklin Stahl and Matthew Meselson invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
Describing his first meeting with James Watson and Matthew Meselson.
Describing how he first met Matthew Meselson.
Sydney Brenner showed that mRNA was the unstable intermediate that carried the message from DNA to the ribosomes.
Francis Crick describes RNA and its role and Paul Zamecnick explains protein synthesis.
Recounting how the seminal "Meselson-Stahl" experiment was only performed 3 times, with one set of results discarded due to mislabelled tubes!
"Courses in eugenics, University of Pittsburgh" (1)