Video 20: Frank Stahl, clip 2
Frank Stahl is a Professor of Biology at the University of Oregon. His current research deals with characterizing and comparing the genetic recombination systems of yeast and coliphage.
matthew meselson, genetic recombination, research deals, university of oregon, biology, stahl, yeast, current research
- ID: 16455
- Source: DNALC.DNAFTB
- Download: MPEG 4 Video
Describing his first meeting with James Watson and Matthew Meselson.
Recounting how the seminal "Meselson-Stahl" experiment was only performed 3 times, with one set of results discarded due to mislabelled tubes!
On whether, upon completing their seminal experiment, Max DelbrÃ¼ck locked Meselson and Stahl in a cabin to force them to write up their results for publishing - how the great scientists are always looking to the "next result."
Comparing the early days of molecular biology research to today's informatics - heavy genome era.
Advice for young, aspiring scientists.
Franklin Stahl and Matthew Meselson invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
Matthew Meselson and Franklin Stahl invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
How Meselson came to read the Watson and Crick paper, then think about ways to experimentally test how DNA replicates.
Explaining density gradient centrifugation.
The three models of DNA replication - semi-conservative, conservative, and dispersive - and whether bias played a role in designing/interpreting the experiment.