DNA ligation, 3D animation with no audio
Once scientists could cut DNA, they still needed a way to paste DNA strands together at will. Arthur Kornberg's identification of an enzyme he called ligase allowed scientists to paste the ends of DNA molecules together. (DNAi Location: Manipulation > Revolution > pieces of the puzzle > DNA ligation)
This animation shows the alignment of matching sticky ends (in pink and red) and the remaking of the sugar-phosphate bonds that form the backbone of DNA by DNA ligase (in green).
dna ligation,restriction enzymes,dna ligase,restriction digest,backbone of dna,sticky ends,pieces of the puzzle,3d animation,dnai,phosphate,alignment,manipulation,bonds
- ID: 15487
- Source: DNALC.DNAi
15488. Restriction digest, 3D animation with no audio
Restriction enzymes can bind to and cut DNA at specific sites.
15541. DNA ligase joining two lengths of DNA at their sticky ends
Once scientists could cut DNA, they still needed a way to paste DNA strands together at will.
15476. Mechanism of Recombination, 3D animation with with basic narration
Genetic engineering: inserting new DNA into a plasmid vector.
16529. Animation 24: The RNA message is sometimes edited.
Rich Roberts and Phil Sharp explain restriction enzymes, electrophoresis, and split genes.
15505. Synthesizing human insulin using recombinant DNA, 3D animation with no audio
Synthesizing human insulin using recombinant DNA, 3D animation with no audio
16705. Animation 34: Genes can be moved between species.
Stanley Cohen and Herbert Boyer transform bacteria with a recombinant plasmid, and Doug Hanahan studies induced transformation.
15917. Cutting and pasting DNA
The discovery of enzymes that could cut and paste DNA made genetic engineering possible.
15493. The double helical structure of DNA, 3D animation with no audio
Animation of 2D DNA model becoming three dimensional.
16723. Problem 34: Genes can be moved between species.
Use green fluorescent protein to tag expression of genes.
15022. How the first recombinant DNA was created, Paul Berg
Paul Berg speaks about his student Janet Mertz's experiment to make the first recombinant DNA molecule.