Translating the genome and Russian prose, Ewan Birney

Interviewee: Ewan Birney. Ewan Birney, a key figure in the public sequence analysis, talks about trying to find meaning in the sequence. (DNAi Location: Genome > The project > Players>Technology > Understanding the masterpiece)

The analogy I use is that the genome is a bit like a big, thick, meaty Russian book. It looks really important, it's written by a great author like Leo Tolstoy, it's War And Peace, you open it up and it's in Russian. And really you need to get the English translation of that book to really understand what's in it. And that's what the process of finding genes is all about, it's effectively making that English translation, that understandable, useful way of viewing this very thick, huge tome that we get out.

russian prose,leo tolstoy,birney,dnai,russian book,war and peace,interviewee,sequence analysis,analogy,masterpiece,genes,dna,translation

Related Content

15305. Compiling the data from the Human Genome Project, Jim Kent

Jim Kent, the author of the assembly program for the public sequence, talks about the challenge of reassembling the genome.

  • ID: 15289
  • Type: video
  • Source: DNAi

15306. The difficulties of DNA assembly, Jim Kent

Jim Kent talks about the difficulties of DNA assembly.

  • ID: 15289
  • Type: video
  • Source: DNAi

11460. Russian immigrants at Ellis Island

Russian immigrants at Ellis Island

  • ID: 15289
  • Type: video
  • Source: EA

15293. How the information in the human genome is stored and expressed, Ewan Birney

Ewan Birney, one of the leading analysts involved in the Human Genome Project, takes you on an informal tour of a chromosome.

  • ID: 15289
  • Type: video
  • Source: DNAi

15291. Finding genes in the human genome, Ewan Birney

For the first draft of the genome sequence, both teams were working to identify the number of human genes. Here, Ewan Birney, a "numbers man" from the public genome project, explains how genes can be recognized and the data from the genome project used.

  • ID: 15289
  • Type: video
  • Source: DNAi

15299. Changing biology with the Human Genome Project, Ewan Birney

Ewan Birney, a key player in the computing and analysis of the genome, reflects on the implications of the Human Genome Project for biology.

  • ID: 15289
  • Type: video
  • Source: DNAi

15290. Finding genes, Ewan Birney

Ewan Birney talks about finding genes.

  • ID: 15289
  • Type: video
  • Source: DNAi

15288. Developing programs that look at DNA sequence, Ewan Birney

Ewan Birney talks about developing programs that look at DNA sequence.

  • ID: 15289
  • Type: video
  • Source: DNAi

15037. The genome is the script, Patrick Brown

Pat Brown draws an analogy between the genome and a script that tells a cell how to behave.

  • ID: 15289
  • Type: video
  • Source: DNAi

11491. Russian giant at Ellis Island (Photograph by Augustus Sherman)

Russian giant at Ellis Island (Photograph by Augustus Sherman)

  • ID: 15289
  • Type: video
  • Source: EA