Developing programs that look at DNA sequence, Ewan Birney
Interviewee: Ewan Birney. Developing programs that look at DNA sequence.
I was looking at sort of theoretical ways or practical ways of dealing with the information in DNA sequence, so I was trying to develop programs that looked at DNA sequence. We didn't have as much DNA as we have now, but we still had enough to sort of get our teeth into. So we were looking at how to build algorithms up, that let us understand DNA sequence. And of course when the Human Genome Project came along, that was an important part of actually understanding this massive, massive data set and making it useful for everybody else to use.
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Ewan Birney talks about finding genes.
For the first draft of the genome sequence, both teams were working to identify the number of human genes. Here, Ewan Birney, a "numbers man" from the public genome project, explains how genes can be recognized and the data from the genome project used.
Ewan Birney, one of the leading analysts of the Human Genome Project, takes you on a chromosome tour.
Ewan Birney talks about processing sequencing data.
Ewan Birney, a key player in the computing and analysis of the genome, reflects on the implications of the Human Genome Project for biology.
Techniques to read the sequence of DNA, letter by letter, have been available since the 1970s. However, the massive task of sequencing the three billion basepairs of the human genome required machines that could read and interpret the data.
Dr. Ewan Birney is a bioinformatician and worked on the Human Genome Project.
Ewan Birney talks about the computers involved in processing DNA data.
Commentators on the genome sequence (Human Genome Project). Top: William Clinton, Ewan Birney, John Sulston. Bottom: Jim Watson, Craig Venter.
Ewan Birney talks about a career in bioinformatic.