Who named messenger RNA?, FranÃ§ois Jacob
Interviewee: FranÃ§ois Jacob. FranÃ§ois Jacob talks about how he and Jacques Monod named messenger RNA. (DNAi Location: Code > Copying the code > Players > FranÃ§ois Jacob > Who came up with messenger RNA?)
It was in a discussion between us but we came out with that, yes, yes. The idea was there were, there was a message, why not messenger, yes, why not messenger.
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François Jacob, Sydney Brenner and Matt Meselson worked on the role of mRNA. An on/off switch involving mRNA seemed a logical control point for protein production.
François Jacob explains why Jacques Monod chose to work with the lactose system.
François Jacob talks about the relationship between DNA, ribosomes, and protein production.
François Jacob talks about bacterial mutants that could not metabolize lactose. Using these mutants, Jacob and Monod figured out how protein production is controlled.
François Jacob talks about how enzyme production was viewed at the time they were beginning their experiments.
François Jacob talks about Genes control the structure of proteins
Matt Meselson also had a hand in Sydney Brenner's RNA experiment. He talks about the experiment and how they waited for James Watson's group to finished their RNA work before publishing.
François Jacob (1953) and Jacques Monod
Translation: RNA to protein, 3D animation with no audio
In this first of a two-part clip, Sydney Brenner describes the information transfer problem from DNA to the protein-making machinery.