Audacious idea of sequencing the human genome?, Leroy Hood
Interviewee: Leroy Hood. Audacious idea of sequencing the human genome ?
Well if you think about the most important observation that came out of Watson and Crick's structure of DNA, it is that DNA is a digital code, a code that's embedded on 24 digital strings in the human. And the idea that you could actually read out the digital information that was the very core source code for human development, was an enormously exciting idea. And up until that time people tended to think much more in terms of maybe we can sequence very, very small genes if we spend a lot of time working. But the audacious idea that you could sequence many genes and even more important ultimately that you could sequence the entire genome, moved our ability to think about deciphering the digital information of our chromosomes in a very, very different direction.
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James Watson talks about the Human Genome Project and government funding.
Leroy Hood talks about DNA sequencing.
James Watson talks about human Genome Project and the future.
James Watson talks about from the double helix to the Human Genome Project.
James Watson and Francis Crick solved the structure of DNA. Other scientists, like Rosalind Franklin and Maurice Wilkins, also contributed to this discovery.
James Watson describes sequencing the human genome using markers and BACs, and Craig Venter explains using cDNA libraries, ESTs, and shotgun sequencing.
Leroy Hood talks about biological source codes.
James Watson and Francis Crick, Cambridge University, 1953
James Watson talks about the Central Dogma: transcription and translation.
James Watson talks about technology and the Human Genome Project.