On the phenomenon of restriction, Paul Berg

Interviewee: Paul Berg. Paul Berg speaks about Herbert Boyer's research into the process by which an organism, such as a bacterium, can recognize and destroy foreign DNA. (DNAi Location: Manipulation > Techniques > Cutting & Pasting > Interviews > On the phenomenon of restriction)

Boyer, Herb Boyer had been studying restriction, the phenomenon of restriction. And he, along with a few others, realized and discovered that restriction, restriction was defined as if you took DNA from one organism and put it into another they destroyed it. But if you took their own DNA and put it in, it went in and survived, so there, there had to be some way in which a given organism recognized its own DNA and also recognized somebody else's DNA as being foreign and destroyed it.

herbert boyer,manipulation techniques,recombinant dna,paul berg,dnai,interviewee,bacterium,restriction,organism,phenomenon

Related Content

15024. The origin and utility of recombinant DNA, Paul Berg

Paul Berg discusses the usefulness of recombinant DNA to isolate and study genes.

  • ID: 15024
  • Source: DNAi

15022. How the first recombinant DNA was created, Paul Berg

Paul Berg speaks about his student Janet Mertz's experiment to make the first recombinant DNA molecule.

  • ID: 15022
  • Source: DNAi

15018. Outrage over recombinant DNA, Paul Berg

Paul Berg's student, Janet Mertz, planned an experiment that would recombine DNA from a monkey virus with DNA from a bacterium that lives in the human gut. Berg describes colleague Bob Pollack's outrage at this.

  • ID: 15018
  • Source: DNAi

15074. Taking apart plasmid DNA, Stanley Cohen

Stanley Cohen speaks about his and Herbert Boyer's experiment to make the first plasmid that had been engineered to contain foreign DNA.

  • ID: 15074
  • Source: DNAi

15030. Implications of recombinant DNA work, Herbert Boyer

Herb Boyer reflects on the importance of their work on rDNA technology and its impact on understanding the genetics of higher organisms.

  • ID: 15030
  • Source: DNAi

15023. The experiment that galvanized the scientific community, Paul Berg

Paul Berg talks about why experiments with recombinant DNA set off a firestorm of controversy, including a moratorium on further experimentation with rDNA.

  • ID: 15023
  • Source: DNAi

15915. The first recombinant DNA

Stanley Cohen and Herbert Boyer's historic experiment used techniques to cut and paste DNA to create the first custom-made organism containing recombined or "recombinant" DNA.

  • ID: 15915
  • Source: DNAi

15020. Possible dangers of recombinant DNA, Paul Berg

Paul Berg talks about possible dangers of recombinant DNA.

  • ID: 15020
  • Source: DNAi

15017. Reaction to outrage over recombinant DNA, Paul Berg

Paul Berg recollects his reaction to his colleague Bob Pollack's opposition to experimentation with recombinant DNA.

  • ID: 15017
  • Source: DNAi

15028. Interest in plasmids, Herbert Boyer

Herb Boyer talks about Stanley Cohen's and his interest in plasmids as vectors for DNA.

  • ID: 15028
  • Source: DNAi