Possible dangers of recombinant DNA, Paul Berg
Interviewee: Paul Berg. Possible dangers of recombinant DNA.
And then there were a series of "what-ifs" if you will, people imagined of how this could be dangerous. Could you put a toxin gene clostridium botulinum toxin gene into E. coli, then you might have an E. coli that's producing a dangerous toxin and that would certainly be undesirable.
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- ID: 15020
- Source: DNALC.DNAi
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15021. The moratorium letter regarding risky experiments, Paul Berg
In 1974, scientists in the field of recombinant DNA drafted a letter calling upon "scientists throughout the world" to suspend certain types of studies until hazards could be assessed. Paul Berg talks about the "Moratorium Letter."
15023. The experiment that galvanized the scientific community, Paul Berg
Paul Berg talks about why experiments with recombinant DNA set off a firestorm of controversy, including a moratorium on further experimentation with rDNA.
15024. The origin and utility of recombinant DNA, Paul Berg
Paul Berg discusses the usefulness of recombinant DNA to isolate and study genes.
15018. Outrage over recombinant DNA, Paul Berg
Paul Berg's student, Janet Mertz, planned an experiment that would recombine DNA from a monkey virus with DNA from a bacterium that lives in the human gut. Berg describes colleague Bob Pollack's outrage at this.
15022. How the first recombinant DNA was created, Paul Berg
Paul Berg speaks about his student Janet Mertz's experiment to make the first recombinant DNA molecule.
15019. Cohesive (sticky) ends and their significance in genetic engineering, Paul Berg
Paul Berg talks about cohesive (sticky) ends and their significance in genetic engineering.
15025. On the phenomenon of restriction, Paul Berg
Paul Berg speaks about Herbert Boyer's research into the process by which an organism, such as a bacterium, can recognize and destroy foreign DNA.
15017. Reaction to outrage over recombinant DNA, Paul Berg
Paul Berg recollects his reaction to his colleague Bob Pollack's opposition to experimentation with recombinant DNA.
15647. Paul Berg (1976)
Image of Paul Berg, Brooklyn-bred chemistry whiz. Known for his pioneering work in recombinant DNA, which won him a Nobel Prize in 1980.
15653. Asilomar meeting
Asilomar meeting. February 1975. (L to R) Maxine Singer, Norton Zinder, Sydney Brenner, Paul Berg.