Experience Alters Gene Expression
Professor Eric Kandel explains that events in the environment can have profound effects on gene expression and brain anatomy.
One of the astonishing things to emerge from the study of learning and memory is that genes are not simply the masters of behavior, the controllers of behavior, they are also the servants of environment. When you learn something and put it into long-term memory, you alter gene expression, giving rise to alterations in the anatomy of the brain. When an environmental event occurs, like a catastrophe, it has profound effects on gene expression in the brain and on anatomical changes in the brain.
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Learning and memory are two intimately linked cognitive processes that stem from interactions with the environment (experience).
Professor Eric Kandel compares short-term memory, which involves the alteration of pre-existing proteins, and long-term memory, which involves new protein synthesis.
Professor Eric Kandel explains how that as you view this interview - the structure of your brain is changing.
Professor Eric Kandel discusses the importance of the hippocampus in the formation of long-term memories.
Professor Eric Kandel discusses changes in synapse structure during long-term memory. Research indicates these changes are synapse-specific and not neuron-wide.
Professor Eric Kandel explains that although identical twins have identical genes, different life experiences mean they do not have identical brains.
Professor Seth Grant explains that long-term memories are created when the synapse sends a signal to the nucleus to activate certain genes.
Professor Ron Davis explains that the gene CREB is important to memory. Blocking CREB expression, blocks short-term memory formation.
Professor Eric Kandel explains that the CA1 region of the hippocampus is important for representing and remembering spaces.
Professor Eric Kandel discusses the importance of attention in forming declarative/explicit memories. These memories involve the hippocampus.