CA1 and Spatial Memory
Professor Eric Kandel explains that the CA1 region of the hippocampus is important for representing and remembering spaces.
The hippocampus proper has three regions: Dentate gyrus, CA3, and CA1. CA1 is closer to the output region of the hippocampus and it is important for representing space in the environment, so that individual cells in the CA1 region encode for space and therefore long-term memory for space and attentional modulation of space importantly involves the CA1 region. If you produce a genetic lesion in some of the critical signaling pathways that are involved in memory storage, and do so selectively in the CA1 region, you interfere with memory storage.
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Professor Eric Kandel discusses the importance of the hippocampus in the formation of long-term memories.
Professor Eric Kandel discusses the importance of attention in forming declarative/explicit memories. These memories involve the hippocampus.
Professor Eric Kandel explains how a protein called CPB may have a built-in memory mechanism that can help long-term memory storage.
Professor Eric Kandel describes how he came to study the model organism Aplysia, which would later earn him a Nobel prize.
The dentate gyrus is one of the few regions in the brain where adult neurogenesis has been confirmed. It may play an important role in translating neural codes for creating memories.
Learning and memory are two intimately linked cognitive processes that stem from interactions with the environment (experience).
The hippocampus is closely aligned to memory formation. It is an important early storage place for long–term memory, and is involved in the transition to more enduring permanent memory.
Professor Eric Kandel discusses the attributes that make Aplysia, a type of sea slug, an ideal model for studying learning and memory.
Professor Eric Kandel explains how that as you view this interview - the structure of your brain is changing.
Professor Eric Kandel discusses changes in synapse structure during long-term memory. Research indicates these changes are synapse-specific and not neuron-wide.