Differences Between Schizophrenia and Bipolar Disorder (3)
Professor David Lewis discusses the differences between schizophrenia and bipolar disorder, noting that there here may be some shared risk factors.
Two illnesses that occur commonly are schizophrenia and bipolar disorder. One of the major advances that was made, now a century ago by Kraepelin, was to discriminate these two disorders based upon certain of their features, but also their life course. For many individuals, when they first present with symptoms, what we call the cross-sectional appearance or the appearance of the symptoms at a given point in time, can be quite similar between schizophrenia and bipolar illness. Itâ€™s only as we follow individuals over time do we begin to see the different courses of the illness and can make the discrimination between the two. Now, on the other hand, genetic studies now are showing that for a least certain genes, risk is increased for both schizophrenia and bipolar disorder. So there may be some shared risk factors for those two illnesses, which may perhaps account for why, clinically, there are certain similarities between the illnesses.
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Doctor Ellen Leibenluft discusses the similarities between schizophrenia and bipolar disorder, which have some genetic risk factors in common.
An overview of schizophrenia-related content on Genes to Cognition Online.
An overview of bipolar disorder-related content on Genes to Cognition Online.
Professor David Lewis outlines how model organisms such as mice can help uncover the interplay of the genetic components in schizophrenia.
Professor David Lewis explains that schizophrenic individuals can have coordination problems, which may relate to impaired neural circuits.
Doctor Anil Malhotra discusses the search for genes in both bipolar disorder and schizophrenia, both of which are in their infancy.
Professor David Porteous predicts that gene medicines such as gene therapy will improve the effectiveness of treating psychiatric disorders.
Doctor Daniel Pine estimates that approximately 30-50% of the risk for anxiety and depression is genetic. Genetic treatments are an exciting area of research currently.
Professor Pat Levitt discusses that although it shares genes with other disorders, schizophrenia is likely caused by unique combinations of genes.
Professor David Lewis discusses how the diversity of symptoms in schizophrenia is reflected in the diversity of genetic and neural causes of the disorder.