Diagnosis, Pathology: Demarzo clip 1
Professor Angelo De Marzo explains that every laboratory test in a hospital is run in theory by pathologists, and so they actually are responsible for the output of every lab value.
Angelo De Marzo M.D., Ph.D. is a pathologist at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. His current research focuses on the inflammatory response and its link to prostate cancer. The research may lead to new diagnostic tests for early detection. â€œEvery laboratory test in the hospital is run in theory by pathologists, and so they actually are responsible for the output of every lab value, even blood, blood work, serum analyses and what not. The type of pathologist that I am that actually is fairly common that people would know about or maybe not know about or maybe they donâ€™t know about is a surgical pathologist. So if you think about at Hopkins we have maybe 30 operating rooms. Every single specimen from a little tiny piece of skin to a very large tumor mass ends up in the department of surgical pathology. The surgeons never make their own diagnosis anymore. In the early 1900s they did; now what they do is they take out the specimen, it goes to pathology, surgical pathology, the pathologist or technician will basically slice up that specimen into a portion that will ultimately be looked at under a microscope. And then the surgical pathologist looks at it under the microscope and decides yes, this is benign, this is malignant, or is cancer or is not. So every diagnosis of a piece of tissue is done by a surgical pathologist. There is another branch of pathology called cytopathology. And there instead of looking at whole pieces of tissue we look at individual cells. So a surgeon or clinician might stick a needle into a lesion and pull out individual cells and smear them on a slide and that way you have individual cells that a cytopathologist looks at and can determine whether it is benign or malignant for instance.â€
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- ID: 1006
- Source: DNALC.IC
1005. Diagnosis, Pathology
Pathology has long been associated with medical development and patient treatment and care. Throughout history pathologists have been trained to observe and recognize abnormalities to diagnose and treat the condition.
1007. Diagnosis, Pathology: Demarzo clip 2
Professor Angelo De Marzo explains that special dyes are utilized to stain cells and when we look at the stained cells under the microscope we look for changes in the architecture of cells.
1008. Diagnosis, Pathology: Demarzo clip 3
Professor Angelo De Marzo explains that if you think about the cells as a community of people, normal people would be a group of students in a lecture that are kind of sitting with their shirts and ties nice and orderly.
983. Causes, Diet: Cause, Nelson
Professor Nelson explains that GSTP1 doesn't seem to be a gene in prostate cancer at least that's controlling growth, invasion, or metastasis.
979. Causes, Diet: Diet and Cancer, Nelson clip 1
Professor Nelson discusses how ecological epidemiology evidence is utilized to determine cancer susceptibility.
981. Causes, Diet: Diet and Cancer, Nelson clip 3
Professor Nelson explains that the prostate is actually a male sex accessory gland that contributes about a third of the secretions to the ejaculate for sexual reproduction.
980. Causes, Diet: Diet and Cancer, Nelson clip 2
Professor Nelson explains that there's something about diets of people who get prostate cancer that are a little different from the diets of people that don't.
985. Causes, Diet: Prevention, Nelson
Professor Nelson explains that chlorophyll is a remarkable energy scavenger and that there is some hint that if you consume chlorophyll you can intercept chemical species, that damage proteins, DNA, and RNA.
982. Causes, Diet: Cause
Meat cooked at high temperatures can produce chemicals that are damaging to cells and DNA.
1025. Causes, Diet
In order to identify cancer causes and prevention strategies, researchers conduct a cohort of studies where they collect information from large groups of individuals over many years.