DISC1 Gene
Disrupted in Schizophrenia 1 (DISC1) is a candidate gene for schizophrenia.
Related Content
512. Identifying the DISC1 Gene
Professor David Porteous describes how his group was first alerted to the DISC1 gene, which was found in a family with a pedigree of schizophrenia and psychoses.
868. Candidate Genes for Schizophrenia
An interactive chromosome map of the genes and loci associated with schizophrenia.
514. Discovery of the DISC1 Gene
Professor David Porteous discusses how his group discovered the DISC1 gene, which is a balanced translocation between chromosomes 1 and 11.
511. RGS4 Gene
Regulator of G-Protein Signaling 4 (RGS4) is a candidate gene for schizophrenia.
510. GRM3 Gene
Metabotropic Glutamate Receptor-3 (GRM3) is a candidate gene for schizophrenia.
509. PPP1R1B Gene
Protein Phosphatase 1, Regulatory Subunit 1B (PPP1R1B) is a candidate gene for schizophrenia.
515. Function of the DISC1 Gene
Professor David Porteous describes how his group is trying to uncover the function of the DISC1 gene.
1242. Translocation
Professor David Porteous explains that a translocation is the relocation of part of one chromosome to a another chromosome.
1431. CAMP Signaling Network
Doctor Josh Dubnau explains that the cyclic AMP (cAMP) signaling network can receive signals from outside the cell and use the signal to alter the function of the cell.
1249. Gene Medicine
Professor David Porteous predicts that gene medicines such as gene therapy will improve the effectiveness of treating psychiatric disorders.