GRM3 Gene
Metabotropic Glutamate Receptor-3 (GRM3) is a candidate gene for schizophrenia.
Metabotropic Glutamate Receptor-3 (GRM3) is a G-protein coupled receptor for glutamate, a major excitatory neurotransmitter. GRM3 also modulates serotonin and dopamine transmission. Several association studies have linked GRM3 polymorphisms to schizophrenia, suggesting functional changes in glutamate transmission in the prefrontal cortex and hippocampus.
schizophrenia, gene, candidate, GRM3, grm, metabotropic, glutamate, Receptor-3, g protein coupled receptor, g protein, dopamine, cyclic amp, c-amp, camp, guanine, polymorphisms, gtp
- ID: 510
- Source: DNALC.G2C
Related Content
868. Candidate Genes for Schizophrenia
An interactive chromosome map of the genes and loci associated with schizophrenia.
511. RGS4 Gene
Regulator of G-Protein Signaling 4 (RGS4) is a candidate gene for schizophrenia.
1365. CREB1 Gene
The cAMP response element-binding protein 1 (CREB1) gene is a CREB activator and has been found to facilitate long-term memory formation.
1366. CREB2 Gene
CAMP response element-binding protein 2(CREB2) is also known as Activating Transcription Factor 2 (ATF2). CREB2 is a CREB repressor, which means it inhibits long-term memory formation.
509. PPP1R1B Gene
Protein Phosphatase 1, Regulatory Subunit 1B (PPP1R1B) is a candidate gene for schizophrenia.
1390. Genes for Learning and Memory
An interactive chromosome map of the genes and loci associated with learning and memory.
1431. CAMP Signaling Network
Doctor Josh Dubnau explains that the cyclic AMP (cAMP) signaling network can receive signals from outside the cell and use the signal to alter the function of the cell.
1173. Glutamate and Schizophrenia
Professor Daniel Weinberger discusses evidence from a number of research areas that highlight the importance of the neurotransmitter glutamate in schizophrenia.
923. DAOA/G72
Polymorphisms of DAOA are associated with schizophrenia and bipolar disorder risk.
1277. Molecules for Memory
Communication in brain cells is guided by interactions between genes and biochemicals at the synapse. These interactions can lead to the formation of new synapses.