Video 33: Walter Gilbert, clip 3

Walter Gilbert is the Carl M. Loeb University Professor at Harvard University. In 1980, he won a Nobel Prize in Chemistry for his work on DNA sequencing.

nobel prize in chemistry, jacob and monod, walter gilbert, dna sequencing, harvard university, loeb, proteins,

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16697. Video 33: Walter Gilbert, clip 4

How Jacob and Monod showed the existence of the inhibitor (what Gilbert calls the repressor).

  • ID: 16697
  • Source: DNAFTB

16698. Video 33: Walter Gilbert, clip 5

Jacob and Monod never identified the inhibitor, but Gilbert found it.

  • ID: 16698
  • Source: DNAFTB

16694. Video 33: Walter Gilbert, clip 1

Before Jacob and Monod, people thought the amount of protein in a cell was constant and proteins turned themselves off.

  • ID: 16694
  • Source: DNAFTB

16695. Video 33: Walter Gilbert, clip 2

Jacob and Monod discovered that genes control the amount of protein in a cell.

  • ID: 16695
  • Source: DNAFTB

16700. Video 33: Walter Gilbert, clip 7

To explain their data, Jacob and Monod had to hypothesize the existence of mRNA.

  • ID: 16700
  • Source: DNAFTB

16699. Video 33: Walter Gilbert, clip 6

What we know about gene regulation today.

  • ID: 16699
  • Source: DNAFTB

16526. Biography 23: Frederick Sanger (1918-2013)

Frederick Sanger received two Nobel prizes (in the same category), for his work on protein sequencing and DNA sequencing.

  • ID: 16526
  • Source: DNALC.DNAFTB

15884. The lac operon

Francois Jacob and Jaçques Monod figured out how bacteria controlled the production of an enzyme called beta-galactosidase. This system of feedback and negative regulation became the lac operon and was the first model for the control of protein productio

  • ID: 15884
  • Source: DNALC.DNAi

15927. Isolating DNA to make human insulin

Walter Gilbert's group tried to isolate the human insulin DNA sequence using the rat insulin DNA sequence.

  • ID: 15927
  • Source: DNAi

16702. Biography 33: François Jacob (1920 - )

François Jacob and Jacques Monod were the first to discover how genes were turned on and off.

  • ID: 16702
  • Source: DNALC.DNAFTB