The lac operon
Francois Jacob and Jaçques Monod figured out how bacteria controlled the production of an enzyme called beta-galactosidase. This system of feedback and negative regulation became the lac operon and was the first model for the control of protein production. Walter Gilbert and his group later isolated the lac operon repressor.
françois jacob and jacques monod,lac operon,jacques monod,françois jacob,beta galactosidase,protein production,walter gilbert,first model,repressor,bacteria
- ID: 15884
- Source: DNALC.DNAi
François Jacob explains why Jacques Monod chose to work with the lactose system.
François Jacob talks about how enzyme production was viewed at the time they were beginning their experiments.
The first model for the control of protein production was the lac operon. This system of feedback and negative regulation is used by bacteria, however, the general principles also apply to higher organisms. Another method of protein regulation involves
FranÃ§ois Jacob's letter to Matt Meselson about his planned trip to Meselson's lab.
François Jacob talks about bacterial mutants that could not metabolize lactose. Using these mutants, Jacob and Monod figured out how protein production is controlled.
François Jacob talks about Genes control the structure of proteins
François Jacob and Jacques Monod were the first to discover how genes were turned on and off.
François Jacob (1953) and Jacques Monod
Jacques Monod and François Jacob work with how bacteria breaks large sugars into smaller pieces.
Jacques Monod and François Jacob were the first to discover how genes were turned on and off.