Maps and markers
The critical first step to mapping the genome involved finding genetic markers. These markers are unique sequences that provide orientation points in the genome landscape.
- ID: 15908
- Source: DNALC.DNAi
15128. Importance of genetic maps, Mary-Claire King
Mary-Claire King talks about the tedious process of hunting for genes in the days before genetic maps (based on thousands of markers) were readily available.
15477. The public Human Genome Project: mapping the genome, sequencing, and reassembly. 3D animation.
The public Human Genome Project: mapping the genome, sequencing, and reassembly.
16832. Problem 39: A genome is an entire set of genes.
Locate a disease gene by screening for markers linked to the gene.
16812. Animation 39: A genome is an entire set of genes.
James Watson describes sequencing the human genome using markers and BACs, and Craig Venter explains using cDNA libraries, ESTs, and shotgun sequencing.
15343. The first draft of the human genome, Ari Patrinos
Ari Patrinos talks about the first draft of the human genome.
15367. Using data from the public project, Craig Venter
Craig Venter, leader of the private effort at Celera Genomics, speaks about his company's reliance on the public data for reassembly of the Celera sequence.
15891. DNA sequencing game, interactive 2D animation
DNA sequencing interactive game. Reconstruct a piece of DNA using the fragments above. We've given you the first piece. You do the rest...
15566. Model organisms (yeast, bacteria, mouse, fruit fly)
Model organisms such as yeast, bacteria, the mouse and the fruit fly are used by researchers to study biological systems. The genomes of these organisms have been mapped and sequenced.
15989. Marker Animation
Watch the animation to learn more about why genetic markers offer important clues in the hunt for genes.